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Nitrogen generator for the pharmaceutical industry

Pharmaceutical plants work to strict standards for purity, safety and compliance. A nitrogen generator for the pharmaceutical industry, installed on-site with a hydrogen plant, supports all three. Being inert, nitrogen protects ingredients from oxygen and moisture. Hydrogen is a key reactant in many life-saving drugs.

Our technical team ranks nitrogen blanketing as the most critical use in pharma. Nitrogen from a PSA nitrogen generator protects reactors, tanks and dryers, so APIs keep their potency. It also purges lines carrying solvents like methanol and acetone, keeping fire risk low. Clean rooms use it as an oil-free utility gas. Hydrogen, at 99.9% to 99.9999% purity, drives catalytic hydrogenation into stable drug molecules.

Nitrogen generator for pharmaceutical industry by Nuberg GPD

Nitrogen generator applications in the pharmaceutical industry

API inerting and solvent safety

Nitrogen blankets reactors, storage tanks, centrifuges and dryers, preventing oxidation. It also purges pipelines and vessels, and transfers solvents and powders without contamination.

Drug synthesis with hydrogen

Hydrogenation in the pharmaceutical industry produces APIs like paracetamol, ibuprofen and anti-histamines, and vitamins A, C, E and K. It also makes intermediates for antibiotic, anti-cancer and cardiac drugs.

Packaging and biotech

Nitrogen flushes vials, ampoules, blisters and drug bags, extending shelf life. It keeps bioreactors anaerobic for antibiotic and vaccine production, and breaks vacuum in freeze dryers.

QC labs and purification

Hydrogen works as a GC carrier gas and fuel gas for GC and GC-MS analysers in QA/QC laboratories. It also reduces metal catalysts, deoxygenates solvents and provides special reducing atmospheres.

A nitrogen generator for the pharmaceutical industry, paired with on-site hydrogen, delivers high-purity APIs with higher yields. Synthesis costs come down too, and products stay stable for longer, which helps plants meet GMP requirements.

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